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This finding, however, contrasts with other meta-analyses that concluded that the GPX1 rs1050450 Pro198Leu polymorphism was not associated with the risk of prostate cancer [154, 155]
In older individuals, age-related changes in hepatic and renal functioning, cognitive functioning, presence of various comorbidities, administration of different drugs, and pharmacokinetics can potentially affect drug-drug interactions and exacerbate underlying medical conditions leading to side effects
doi: 10.1159/000345030
OLT1177 (Dapansutrile), a selective NLRP3 inflammasome inhibitor, ameliorates experimental autoimmune encephalomyelitis pathogenesis